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孙铁东

发布时间:2019-11-13文章来源: 浏览次数:

一、 基本信息

孙铁东,男,1985 年生,中共党员,博士,副教授,硕士生导师。首批黑龙江省优秀青年基金获得者, 江苏省海安市海陵英才计划获得者,黑龙江省化学学会理事。现主持国家自然科学基金等各类科研项目10项,累计科研经费 200 余万元Adv. Mater.ACS Nano J. Mater. Chem. BBiomater. Sci.等国际权威期刊上以第一及通讯作者发表SCI论文20篇,其中IF > 20论文1篇,IF > 10论文2担任ACS Applied Materials & Interfaces, ACS Sustainable Chemistry & Engineering, Acta Biomaterialia等国际期刊审稿人。邮箱:stdhaode@163.com

二、学习工作经历

2015年度以优秀博士生国际交流计划身份赴美国耶鲁大学医学院留学。2016年毕业于哈尔滨工业大学生物医学工程专业,获工学博士学位。20173月以优秀青年学者人才引进方式进入教育部直属211大学东北林业大学从事教学与科研工作。

三、所在学科

学硕:化学(分析化学方向);

专硕:材料与化工(化学工程方向)


四、研究方向

主要从事纳米生物材料在癌症诊疗,生物分析以及催化领域的应用研究


五、科研项目

[1] 超小Keggin型多金属氧酸盐纳米粒子的制备及CT/光声双模态成像指导的胰腺癌光热治疗研究,国家自然科学基金青年项目(51902047),2020.01-2022.1225万,主持。

[2] 生物质基荧光纳米粒子的制备及其在癌症诊疗中的应用,黑龙江省优秀青年基金(YQ2019B001),2019.07-2022.07,主持。

[3] 可视化肿瘤光热治疗用纳米近红外吸收剂的研究,中央高校基本科研业务费专项资金项目(2572018BC11),2018.06-2020.06,主持。

[4] 纤维素基载药纳米粒子的制备及其抗肿瘤活性研究,东北林业大学优秀青年学者引进人才启动基金项目,2017.03-2021.0330万,主持。

[5] 江苏省海安市海陵英才计划,80万,2020-2023,主持。

[6] 新型环保水性印刷材料的研制,乐荟文具南通有限公司,30万,2020-2021,主持。

[7] POM@MOF等微纳米材料生物活性综合测试,哈尔滨工业大学4万,2020-2020主持

[8] POM@COF材料生物活性综合测试哈尔滨工业大学2.9万,2020-2020主持

六、论文发表

[1] T.D. Sun, W. Cui, M. Yan, G. Qin, W. Guo, H.X. Gu, S.Q. Liu*, Q. Wu* Target delivery of a novel antitumor organoplatinum(IV)-substituted polyoxometalate complex for safer and more effective colorectal cancer therapy in vivo, Advanced Materials, 2016, 28, 7397. (IF=27.398)

[2] J.H. Zhou, W.C. Zhao, Z.H. Miao, J.G. Wang, Y. Ma, H.T. Wu, T.D. Sun*, H.S. Qian, Z.B. Zha*, Folin-ciocalteu assay inspired polyoxometalate nanoclusters as a renal clearable agent for non-inflammatory photothermal cancer therapy, ACS Nano, 2020, 14, 2126. (IF=14.588)

[3] W.C. Zhao, J.G. Wang, H.N. Wang, S.T. Lu, Y. Song, H.X. Chen, Y. Ma*, L. Wang*, T.D. Sun*, Combinatorial discovery of Mo-based polyoxometalate clusters for tumor photothermal therapy and normal cell protection, Biomaterials Science, 2020, 8, 6017. (IF=6.183)

[4] S.T. Lu, L.P. Liu, H.N. Wang, W.C. Zhao, Z.Y. Li, Z. Qu, J.L. Li, T.D. Sun*, T. Wang*, G.C. Sui, Synthesis of dual functional gallic-acid-based carbon dots for bioimaging and antitumor therapy, Biomaterials Science, 2019, 7, 3258. (IF=6.183)

[5] G.Q. Tian, W.L. Wang, B.J. Huang, L. Shi, L. Li, J. Xiao, Y.Y. Pan, S.Y. Chen, T. Jia*, T.D. Sun*, A quinacridone derivative with intensive emission in both solution and the solid state via a facile preparation for cell imaging applications, Journal of Materials Chemistry B, 2019, 7, 3192. (IF=5.344)

[6] L. Li, Q. Yang, L. Shi, N.N. Zheng, Z. Li, K. Li, S. Qiao, T. Jia*, T.D. Sun*, Y. Wang, Novel phthalocyanine-based polymeric micelle with high near-infrared photothermal conversion efficiency under 808 nm laser irradiation for in vivo cancer therapy, Journal of Materials Chemistry B, 2019, 7, 2247. (IF=5.344)

[7] Y. Song, Z. Qu, J.B. Li, L. Shi, W.C. Zhao, H.N. Wang, T.D. Sun*, T. Jia*, Y. Sun*, Fabrication of the biomimetic DOX/Au@Pt nanoparticles hybrid nanostructures for the combinational chemo/photothermal cancer therapy, Journal of Alloys and Compounds, 2021, DOI:10.1016/j.jallcom.2021.160592.(IF=4.65)

[8] X.C. Fan, L. Yang, T. Wang*, T.D. Sun*, S.T. Lu, pH-responsive cellulose-based dual drug-loaded hydrogel for wound dressing, European Polymer Journal, 2019, 121, 109290. (IF=3.862)

[9] Z. Qu, L.P. Liu, T.D. Sun*, J. Hou*, Y. Sun*, M. Yu, Y.X. Diao, S.T. Lu, W.C. Zhao, L. Wang*. Synthesis of bifunctional carbon quantum dots for bioimaging and anti-inflammation, Nanotechnology, 2020, 31, 175102. (IF=3.551)

[10] Z.Y. Li, T. Wang*, L.Y. Gu, H.N. Wang, Y.L. Zhao, S.T. Lu, W.C. Zhao, and T.D. Sun*, N-doped carbon dots modified with the epithelial cell adhesion molecule antibody as an imaging agent for HepG2 cells using their ultra-sensitive response to Al3+, Nanotechnology, 2020, 31, 485703. (IF=3.551)

[11] L. Li, W.C. Zhao, Z. Qu, L. Shi, S.N. Tan, E.N. Ha, T. Jia*, T.D. Sun*, Novel phthalocyanine-based micelles/PNIPAM composite hydrogels: spatially/temporally controlled drug release triggered by NIR laser irradiation, New Journal of Chemistry, 2020, 44, 8705 (IF=3.288)

[12] J. Hou, J. Qin, H.Y. Pang, X. Gao, T.D. Sun*, B. Li*, N, S-co-doped carbon dots for rapid acid test paper and bioimaging, RSC Advances, 2020, 10, 41332. (IF=3.119)

[13] H.N. Wang, Z.Y. Li, S.T. Lu, C.Y. Li, W.C. Zhao, Y.L. Zhao, S.L. Yu, T. Wang*T.D. Sun*, Nano micelles of cellulose-graft-poly (l-lactic acid) anchored with epithelial cell adhesion antibody for enhanced drug loading and anti-tumor effect, Materials Today Communications, 2019, 22, 100764. (IF=2.678)

[14] Z.H. Yu, Y. Sun*, T.D. Sun*, T. Wang*, Combined application of nanotechnology and multiple therapies with tumor immune checkpoints, ChemistrySelect, 2020, 5, 14943. (IF=1.811)

[15] Y.X. Bai, Z.Y. Li, L.P. Liu, X.C. Fan, T.D. Sun*, T. Wang*, Z.Z. Gou, S.N. Tan, Tumor-targeting peptide for redox-responsive Pt prodrug and gene codelivery and synergistic cancer chemotherapy, ACS Applied Bio Materials, 2019, 24, 1420.

[16] S.T. Lu, X.C. Fan, H.N. Wang, Y.L. Zhao, W.C. Zhao, M.Z. Li, R.Y. Lv, T. Wang*, T.D. Sun*, Synthesis of gelatin-based dual-targeted nanoparticles of betulinic acid for antitumor therapy, ACS Applied Bio Materials, 2020, 3, 3518.

[17] E.J. Gao*, T.D. Sun, S.H. Liu, S. Ma, Z. Wen, Y. Wang, M.C. Zhu, L. Wang, X.N. Gao, F. Guan, M.J. Guo, F.C. Liu, Synthesis, characterization, interaction with DNA and cytotoxicity in vitro of novel pyridine complexes with Zn (II), European Journal of Medicinal Chemistry, 2010, 45, 4531. (IF=5.573)

[18] W. Guo, C.S. Guo*, N.N. Zheng, T.D. Sun, S.Q. Liu*, CsxWO3 nanorods coated with polyelectrolyte multilayers as a multifunctional nanomaterial for bimodal imaging-guided photothermal/photodynamic cancer treatment, Advanced Materials, 2017, 29: 1604157. (IF=27.398)

[19] J. Zhao, K.X. Li, K.W. Wan, T.D. Sun, N.N. Zheng, F.J. Zhu, J.C. Ma, J. Jiao, T.C. Li, J.Y. Ni, X.H. Shi, H. Wang, Q. Peng, J. Ai*, W.H. Xu*, S.Q. Liu*, Organoplatinum-substituted polyoxometalate inhibits β-amyloid aggregation for alzheimer’s therapy, 2019, Angewandte Chemie International Edition, 2019, 58, 18032. (IF=12.959)

[20] H.X. Gu, C.S. Guo, S.H. Zhang, L.H. Bi, T.C. Li, T.D. Sun, S.Q. Liu*, Highly efficient, near-infrared and visible light modulated electrochromic devices based on polyoxometalates and W18O49 nanowires. ACS Nano, 2018, 12, 559. (IF=14.588)


教研论文

1. 侯娟,冯伟,孙铁东。如何讲好化工类专业分析化学绪论课。广东化工,201946114.



发明专利

1. 孙铁东李泽宇王霆刁永兴. 具有主动靶向,荧光成像及肿瘤联合治疗功能的聚多巴胺量子点的制备方法及其应用. 专利号:CN201910993579.9


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