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李春英

发布时间:2019-11-13文章来源: 浏览次数:


李春英,女,1976 年生人,博士,副教授,硕士、博士研究生导师,黑龙江省植物学会理事。20009月考入东北林业大学植物学专业攻读硕士研究生,20036月,硕士毕业后留任于东北林业大学工作。2006年博士毕业于东北林业大学生物工程专业。2004年被评为东北林业大学科教对接先进个人称号。2015-2016年美国麻萨诸塞大学达特茅斯分校化学与生物化学系访问学者。主要致力于植物种间关系、植物资源学,药用植物活性成分筛选和功能成分评价等方面的研究。近五年发表学术论文40余篇,出版学术专著2部,获得国家发明专利3项。作为项目主持人承担了国家科技支撑计划课题、黑龙江省、教育部及企业横向等课题10余项。信箱:nefujane@aliyun.com


科学研究方向:

1. 植物活性成分高效分离与功能评价

2. 植物种间关系


所在学科:

药学学科生药学方向(学硕)/植物学(博士点)


近年研究课题:

1. 十三五国家重点研发计划子课题:喜树红豆杉人工混交林营建技术研究(2017YFD060070601-5),2017.07-2020.12,主持人.

2. 黑龙江省留学归国人员科学基金:苘麻根系化学信息物质诱导小麦化感效应的机制(LC2017005),2017.10-2020.10,主持人.

3. 企业横向项目:林蛙油产品加工利用关键技术研究,黑龙江大通生物技术有限公司,2018.5-2022.5 主持人

4. 高等学校博士学科点专项科研基金课题:南方红豆杉taxanes对喜树根系分泌物的响应机制(20130062120015),2014.01-2016.12,主持人.

5. 十二五农村领域国家科技计划课题:羟基喜树碱提取工艺研究(2012BAD21B0501-04),2012.01-2016.12,主持人.

6. 中央高校基本科研业务费专项资金:烟草中茄尼醇特异性累积及其对环境因子响应机制(DL12CA05),2012.05-2015.05,主持人.

7. 林业公益性行业科研专项经费课题:京尼平高效分离研究(2012BAD21B050104),2012.01-2014.12,主持人.

8. 浙江海正药业股份有限公司技术开发项目:木豆高效加工利用工艺研究,2010.01-2012.12,主持人.

9. 黑龙江省自然科学基金项目:烟草中辅酶Q10高效制备的应用基础研究,2011.01-2013.12,主持人.


近年发表的主要学术论文:

1. Chunying Li, Changyin Feng, Mengfei Tian, Xianming Meng, Chunjian Zhao. A Novel approach for echinacoside and acteoside extraction from Cistanche deserticola Y. C. Ma using an aqueous system containing ionic liquid surfactants. Sustainable Chemistry and Pharmacy, 2022, 26: 100644.(SCI)

2. Chunying Li, Xianming Meng, Mengfei Tian, Shen Li, Yao Tian, Chunjian Zhao, Yujie Fu. A novel method to extract juglone from Juglans mandshurica waste branches using a water-in-oil microemulsion. Waste and Biomass Valorization, 2022, 13: 1547–1563.(SCI)

3. Chunying Li, Fang Nie, Changyin Feng, Mengfei Tian, Meiting Yu, Chunjian Zhao*, Yujie Fu*. Magnetic dual-template molecularly imprinted polymers for separation and enrichment of echinacoside and acteoside from Cistanche deserticola Y. C. Ma. Chemical Engineering Research and Design, 2022, 182: 719-732.(SCI)

4. Chunying Li, Meiting Yu, Shen Li, Xue Yang, Bin Qiao, Sen Shi, Chunjian Zhao, Yujie Fu. Valorization of Fig (Ficus carica Linn.) waste leaves: HPLC-QTOF-MS/MS-DPPH system for online screening and identification of antioxidant compounds. Plants, 2021, 10, 2532.(SCI)

5. Chunying Li, Xue Yang, Yao Tian, Meiting Yu, Sen Shi, Bin Qiao, Chunjian Zhao, Liang Mao. The effects of fig tree (Ficus carica L.) leaf aqueous extract on seed germination and seedling growth of three medicinal plants. Agronomy, 2021;11: 2564.(SCI)

6. Chunying Li, Zhicheng Lu, Chunjian Zhao*, Lei Yang, Yujie Fu, Kunming Shi, Xin He, Zhao Li; Yuangang Zu. Ionic-liquid-based ultrasound/microwave-assisted extraction of 2, 4-dihydroxy-7-methoxy-1, 4-benzoxazin-3-one and 6-methoxy-benzoxazolin-2-one from maize (Zea mays L.) seedlings. Journal of Separation Science, 2015, 38(2): 291-300. (SCI).

7. Chunying Li, Yukun, Zhang, Chunjian Zhao, Yujiao Ni, Kaiting Wang, Jingjing Zhang, Wenyan Zhao. Ultrasonic assisted-reflux synergistic extraction of camptothecin and betulinic acid from Camptotheca acuminata Decne. fruits, Molecules 2017, 22(7): 1076, (SCI).

8. Haiyao Sun, Chunying Li, Yujiao Ni, Liping Yao, Hongwei Jiang, Xueting Ren, Yujie Fu, Chunjian Zhao*. Ultrasonic/microwave-assisted extraction of polysaccharides from Camptotheca acuminata fruits and its antitumor activity. Carbohydrate Polymers, 206 (2019) 557–564 (SCI).

9. Chunjian Zhao, Jiabo Cheng, Chunying Li*, Shen Li, Yao Tian, Tingting Wang, Yujie Fu. Quality evaluation of Acanthopanax senticosus via quantitative analysis of multiple components by single marker and multivariate data analysis. Journal of Pharmaceutical and Biomedical Analysis, 2021;201: 114090.(SCI)

10. Chunjian Zhao, Zhao Li, Chunying Li*, Lei Yang, Liping Yao, Yujie Fu, Xin He, Kunming Shi, Zhicheng Lu. Optimized extraction of polysaccharides from Taxus chinensis var. mairei fruits and its antitumor activity, International Journal of Biological Macromolecules, 2015, 75(4): 192-198 (SCI).

11. Chunying Li, Yao Tian, Shen Li, Tingting Wang, Xin Li, Chunjian Zhao, Yujie Fu. Application of fingerprint combined with quantitative analysis and multivariate chemometric methods in quality evaluation of dandelion (Taraxacum mongolicum). Royal Society Open Science. 2021, 8, 210614.(SCI)

12. Chunjian Zhao, Deman Liu; Chunying Li*, Yujie Fu, ; Lei Yang, .; Yuangang Zu. Separation of pinostrobin from pigeon pea [Cajanus cajan (L) Millsp.] leaf extract using a cation exchange resin for catalytic transformation combined with a polyamide resin. Separation and Purification Technology 2014, 133, 168-175. (SCI, IF 3. 927).

13. Lixin Wei, Xin Li, Weiran Su, Chunjian Zhao*, Aoqi Wang, Lingling Dong, Mengfei Tian, Chunying Li*. A novel approach for synchronous transformation and extraction of psoralen from fig (Ficus carica L.) leaves based on polarity of different macroporous adsorption resins. Chemical Engineering Research and Design, 2022, 178: 148-156.(SCI)

14. Sen shi, Yinxiang Gao, Chunying Li *, Jingjing Zhang, Jiajing Guan, Chunjian Zhao, Yujie Fu. Allelopathy of Taxus chinensis var. mairei on Camptotheca acuminata seedling growth and identification of the active principles. Journal of Plant Interactions, 2022, 17: 33–42.(SCI)

15. Bin Qiao, Chunying Li*, Chunyu Liang, Xin Li, Mengfei Tian, Qianqian Li, Chunjian Zhao*, Yujie Fu*. Determination of phenolic acids in Rehmannia glutinosa rhizosphere using a new method of microdialysis-HPLC. South African Journal of Botany, 2022, 148: 387-395.(SCI)

16. Mengfei Tian, Qianqian Li, Wenyan Zhao, Bin Qiao, Sen Shi, Meiting Yu, Xin Li, Chunying Li*, Chunjian Zhao*. Potential allelopathic interference of Abutilon theophrasti Medik. powder/extract on seed germination, seedling growth and root system activity of maize, wheat and soybean. Agronomy, 2022, 12(4):844.(SCI)

17. Chunjian Zhao, Xin Li, Chunying Li*, Shen Li, Yao Tian, Tingting Wang, Yujie Fu. Ingenious application of ethylenediaminetetraacetic acid disodium to improve the extraction yield of psoralen in fig (Ficus carica L.) leaves. Natural Product Research, 2021, 1980792.(SCI)

18. Xue Yang, Yuzheng Li, Chunying Li*, Qianqian Li, Bin Qiao, Sen Shi, Chunjian Zhao. Enhancement of interplanting of Ficus carica L. with Taxus cuspidata Sieb. et Zucc. on growth of two plants. Agriculture, 2021;11: 1276.(SCI)

19. Chunjian Zhao, Shen Li, Chunying Li*, Tingting Wang, Yao Tian, Xin Li, Yujie Fu. Ultrasonic enzyme co-assisted aqueous two-phase extraction and identification of flavonoid compounds from Fig (Ficus carica Linn.) leaves using UPLC-QTOF-MS/MS. Appled Sciences, 2021, 11, 7718.(SCI)

20. Chunjian Zhao, Xueting Ren, Chunying Li*, Hongwei Jiang, Jiajing Guan, Weiran Su, Yuzheng Li, Yao Tian, Tingting Wang and Shen Li. Coupling ultrasound with heat-reflux to improve the extraction of quercetin, kaempferol, ginkgetin and sciadopitysin from Mairei yew leaves, Appl. Sci.2019, 9(4), 795(SCI).

21. Chunying Li, Jingjing Zhang, Chunjian Zhao, Wenyan Zhao, Lei Yang, Hongwei Jiang, Xueting Ren, Weiran Sun, Yuzheng Li, Jiajing Guan.Separation of the main flavonoids and essential oil from seabuckthorn leaves by ultrasonic/microwave assisted simultaneous distillation extraction, Royal Society Open Science, 2018, 5(7) : 180133, (SCI).

22. Chunjian Zhao, Yukun Zhang, Chunying Li*, Xin He, Lei Yang , Yujie Fu, Jingjing Zhang, Wenyan Zhao and Yuangang Zu. Development of an ionic liquid-based ultrasonic/microwave-assisted simultaneous distillation and extraction method for separation of camptothecin, 10-hydroxycamptothecin, vincoside-lactam, and essential oils from the fruits of Camptotheca acuminata Decne, Appl. Sci. 2016, 6, 293; doi: 10.3390/app6100293(SCI).

23. Chunjian Zhao, Xin He, Chunying Li*, Lei Yang , Yujie Fu, Kaiting Wang , Yukun Zhang and Yujiao Ni. A microwave-assisted simultaneous distillation and extraction method for the separation of polysaccharides and essential oil from the leaves of Taxus chinensis var. mairei, Appl. Sci. 2016, 6, 19; doi: 10.3390/app6020019(SCI).

24. Chunjian Zhao, Zhicheng Lu, Chunying Li*, Xin He, Zhao Li, Kunming Shi, Lei Yang, Yujie Fu, Yuangang Zu. Optimization of ionic liquid based simultaneous ultrasonic- and microwave-assisted extraction of rutin and quercetin from leaves of velvetleaf (Abutilon theophrasti) by response surface methodology. The Scientific World Journal, 2014, Article ID: 283024. (SCI)

25. Chunjian Zhao, Shuaihua Liu, Chunying Li*, Lei Yang and Yuangang Zu*. In Vitro Evaluation of the Antiviral Activity of the Synthetic Epigallocatechin Gallate Analog-Epigallocatechin Gallate (EGCG) Palmitate against Porcine Reproductive and Respiratory Syndrome Virus, Viruses 2014, 6(2), 938-950(SCI).

26. Chunjian Zhao, ChunyingLi*, Shuaihua Liu, Lei Yang. The galloyl catechins contributing to main antioxidant capacity of tea made from Camellia sinensis in China. The Scientific World Journal, 2014, Article ID: 863984. (SCI).

27. Chunjian Zhao, Chunying Li, Lei Wang, Yuangang Zu, and Lei Yang. Determination of camptothecin and 10-hydroxycamptothecin in Camptotheca acuminata by lc-esi-ms/mS. Analytical Letters, 2010, 43 2681–2693(SCI).

28. Yao Sun, Fansong Mu, Chunying Li, Wei Wang, Meng Luo, Yujie Fu, Yuangang Zu. Aspidin BB, a phloroglucinol derivative, induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells. Chemico-Biological Interactions, 2013, 204 (2): 88-97(SCI).

29. Fei-Yue Ma, Cheng-Bo Gu, Chun-Ying Li, Meng Luo, Wei Wang, Yuan-Gang Zu, Ji Li, Yu-Jie Fu. Microwave-assisted aqueous two-phase extraction of isoflavonoids from Dalbergia odorifera T. Chen leaves Separation and Purification Technology, 2013, 115(30): 136-144(SCI, IF 3. 927).

30. Chunjian Zhao, Lei Wang, Yuangang Zu, Chunying Li, Shuaihua Liu, Lei Yang, Xiuhua Zhao and Baishi Zu. Micronization of Ginkgo biloba extract using supercritical antisolvent process. Powder technology, 2011, 209(1-3): 73-80(SCI).

31. Chunjian Zhao, Yuangang Zu, Chunying Li. Extraction of solanesol from tobacco (Nicotiana tobaccum L.) leaves by bubble column. Chemical Engineering and Processing. 2009, 48 (1): 203-208 (SCI).

32. Lei Yang, Chunjian Zhao, Chunying Li, Jiahui Li, Xiaojuan Li, Yuangang Zu. Separation by Macroporous Resins of 10-Hydroxycamptothecin from the Remainder Extracts in the Production of Camptothecin. Adsorption Science and Technology, 2009, 27(2): 117-134(SCI).

33. Chunjian Zhao, Chunying Li, Yuangang Zu.Rapid and quantitative determination of solanesol in Nicotiana tabacum by liquid chromatography–tandem mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis, 2007, 44(1): 35-40 (SCI).

34. Xiao-Hui Yao, Dong-Yang Zhang, Yuan-Gang Zu, Yu-jie Fu, Meng Luo, Cheng-Bo Gu, Chun-Ying Li, Fan-Song Mu, Thomas Efferth. Free radical scavenging capability, antioxidant activity and chemical constituents of Pyrola incarnata Fisch. leaves. Industrial Crops and Products, 2013, 49: 247-255(SCI).

35. Ji Li, Meng Luo, Chun-Jian Zhao, Chun-Ying Li, Wei Wang, Yuan-Gang Zu, Yu-Jie Fu. Oil removal from water with yellow horn shell residues treated by ionic liquid. Bioresource Technology, 2013, 128: 673-678 (SCI).

36. Ting-ting Liu, Chun-hui Ma, Xiao-yu Sui, Lei Yang, Yuan-gang Zu, Chun-jian Zhao, Chun-ying Li, Lin Zhang. Preparation of shikonin by hydrolyzing ester derivatives using basic anion ion exchange resin as solid catalyst. Industrial Crops and Products, 2012, Volume 36(1): 47-53(SCI).

37. Shuang Jin, Meng Luo, Wei Wang, Chun-jian Zhao, Cheng-bo Gu, Chun-ying Li, Yuan-gang Zu, Yu-jie Fu, Yue Guan . Biotransformation of polydatin to resveratrol in Polygonum cuspidatum roots by highly immobilized edible Aspergillus niger and Yeast, Bioresource Technology, 2013, 136: 766-770 (SCI).

38. Shuang Jin, Wei Wang, Meng Luo, Fan-Song Mu, Chun-Ying Li, Yu-jie Fu, Yuan-Gang Zu, Chen Feng. Enhanced extraction genistein from pigeon pea [Cajanus cajan (L.) Millsp.] roots with the biotransformation of immobilized edible Aspergillus oryzae and Monacus anka and antioxidant activity evaluation, Process Biochemistry, 2013, 48( 9): 1285-1292(SCI).

39. Li-Li Dong, Yu-Jie Fu, Yuan-Gang Zu, Meng Luo, Wei Wang, Chun-Ying Li, Pan-Song Mu .An enhanced preparation and purification of the major antioxidants baicalein and wogonin from Scutellariae radix , Food Chemistry, 2012, 133( 2): 430-436(SCI).

40. Xiao-Juan Li, Wei Wang, Meng Luo, Chun-Ying Li, Yuan-Gang Zu, Pan-Song Mu, Yu-Jie Fu. Solvent-free microwave extraction of essential oil from Dryopteris fragrans and evaluation of antioxidant activity, Food Chemistry, 2012, 133( 2): 437-444(SCI).

41. Jiao Jiao, Qing-Yan Gai, Yu-Jie Fu, Yuan-Gang Zu, Meng Luo, Chun-Jian Zhao, Chun-Ying Li. Microwave-assisted ionic liquids treatment followed by hydro-distillation for the efficient isolation of essential oil from Fructus forsythiae seed , Separation and Purification Technology, 2013, 107: 228-237(SCI).

42. Qing-Yan Gai, Jiao Jiao, Pan-Song Mu, Wei Wang, Meng Luo, Chun-Ying Li, Yuan-Gang Zu, Fu-Yao Wei, Yu-Jie Fu. Microwave-assisted aqueous enzymatic extraction of oil from Isatis indigotica seeds and its evaluation of physicochemical properties, fatty acid compositions and antioxidant activities, Industrial Crops and Products, 2013, 45: 303-311(SCI).

43. Zuofu Wei, Meng Luo, Chunjian Zhao, Wei Wang, Lin Zhang, Yuangang Zu, Chunying Li, Tingting Li, Yujie Fu. An efficient preparative procedure for main flavone aglycones from Equisetum palustre L. using macroporous resin followed by gel resin flash chromatography. Separation and Purification Technology, 2013, 118(30): 680-689 (SCI).

44. Yuangang Zu, Chunying Li, Yujie Fu, Chunjian Zhao. Simultaneous determination of catechin, rutin, quercetin, kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. Journal of Pharmaceutical and Biomedical Analysis. 2006, 41(3): 714–719 (SCI).

45. Yuangang Zu, Chunjian Zhao, Chunying Li, Lin Zhang. A rapid and sensitive LC-MS-MS method for determination of coenzyme Q10 in tobacco (Nicotiana tabacum L.) leaves. Journal of Separation Science, 2006, 29, 1607-1612(SCI).


代表著作:

1. 李春英,付玉杰,赵春建.药学专业英语,黑龙江科技出版社,2020.12

2. 付玉杰,李春英,王微,王希清. 木豆资源活性成分功能评价。科学出版社,2021.1

3. 李春英,赵春建. 植物色素,黑龙江科技出版社,2012.9



获奖情况:

1. 特色林药提取物高效分离关键技术与推广示范. 黑龙江省科技发明二等奖, 2020, 第三完成人。

2. 木豆资源功能活性成分高值化加工利用关键技术及产业化应用,第八届梁希林业科学技术二等奖, 2017, 第六完成人。

3. 甘草优质栽培及活性成分高效利用,黑龙江省科学技术进步三等奖,2005,第四完成人。

4. 茄尼醇高效提取纯化生产新工艺,中华人民共和国教育部提名技术发明一等奖,第七完成人。

5. 甘草多种有效成分高效提取纯化新工艺,中华人民共和国教育部提名科技进步二等奖,2005,第三完成人。

6. 甘草的优质栽培及活性成分高效利用,黑龙江省高校科学技术二等奖,2015,第四完成人。


获得国家专利情况:

1. 李春英, 赵春建, 付玉杰, 苏伟然, 李玉正, 关佳晶. 红豆杉和无花果树混交林的营造方法, ZL 202010406489.8, 2021年授权.

2. 李春英,赵春建,祖元刚. 一种从烟草中提取辅酶Q10的方法. 发明专利ZL 201110289097.9, 2014年授权.

3. Chunying Li, Chunjian zhao, Yujie Fu, Weiran Su, Yuzheng Li, Jiajing Guan. Method for constructing a mixed forest of yew trees and fig trees, US17/297 204, 2022年授权.



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